Structure of PDB 2fjx Chain A

Receptor sequence

>2fjxA (length=255) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence]

TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVE
DIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWR
DPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYV
DDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLL
KEGQR

3D structure

PDB

2fjx A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine.

Chain

Resolution

1.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Y64 L99 R116	Y41 L76 R93
BS02	dna	A	L99 D114 L115 R116 G191	L76 D91 L92 R93 G168

External links

PDB	RCSB:2fjx, PDBe:2fjx, PDBj:2fjx
PDBsum	2fjx
PubMed	16771498
UniProt	P03355\|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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