Structure of PDB 2fib Chain A

Receptor sequence
>2fibA (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
VQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWT
VFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAI
PYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDG
FDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAG
HLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
3D structure
PDB2fib The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
ChainA
Resolution2.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F295 D297 D301 T305 F322 Q329 K338 C339 H340 D364 F153 D155 D159 T163 F180 Q187 K196 C197 H198 D222
BS02 CA A D318 D320 F322 E323 G324 D176 D178 F180 E181 G182
Gene Ontology
Biological Process
GO:0007596 blood coagulation

View graph for
Biological Process
External links
PDB RCSB:2fib, PDBe:2fib, PDBj:2fib
PDBsum2fib
PubMed9207064
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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