Structure of PDB 2fhe Chain A

Receptor sequence
>2fheA (length=216) Species: 6192 (Fasciola hepatica) [Search protein sequence]
PAKLGYWKIRGLQQPVRLLLEYLGEKYEEQIYERDDGEKWFSKKFELGLD
LPNLPYYIDDKCKLTQSLAILRYIADKHGMIGTTSEERARVSMIEGAAVD
LRQGISRISYQPKFEQLKEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHV
DFMVYEALDAIRYLEPHCLDHFPNLQQFMSRIEALPSIKAYMESNRFIKW
PLNGWHAQFGGGDAPP
3D structure
PDB2fhe Crystallization, structural determination and analysis of a novel parasite vaccine candidate: Fasciola hepatica glutathione S-transferase.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y6 L12
Catalytic site (residue number reindexed from 1) Y6 L12
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A Y6 W7 W40 K44 N53 L54 Q66 S67 Y6 W7 W40 K44 N53 L54 Q66 S67
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity

View graph for
Molecular Function
External links
PDB RCSB:2fhe, PDBe:2fhe, PDBj:2fhe
PDBsum2fhe
PubMed9367777
UniProtP56598|GST29_FASHE Glutathione S-transferase class-mu 26 kDa isozyme 1

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