Structure of PDB 2fci Chain A

Receptor sequence
>2fciA (length=105) Species: 9913 (Bos taurus) [Search protein sequence]
GSPGIHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFR
AEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPIN
EENSS
3D structure
PDB2fci Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.11: phosphoinositide phospholipase C.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R18 A19 R37 R39 N40 F49 K54 I55 K56 C58 R59 L69 G70 N71 Y84 Y90 R18 A19 R37 R39 N40 F49 K54 I55 K56 C58 R59 L69 G70 N71 Y84 Y90
External links
PDB RCSB:2fci, PDBe:2fci, PDBj:2fci
PDBsum2fci
PubMed16410013
UniProtP08487|PLCG1_BOVIN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (Gene Name=PLCG1)

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