Structure of PDB 2f4o Chain A

Receptor sequence
>2f4oA (length=290) Species: 10090 (Mus musculus) [Search protein sequence]
GDSTILKVLQSNIQHVQLYENPVLQEKALTCIPVSELKRKAQEKLFRARK
LDKGTNVSDEDFLLLELLHWFKEEFFRWVNNIVCSKCGGETRSRDEALLP
NDDELKWGAKNVENHYCDACQLSNRFPRYNNPEKLLETRCGRCGEWANCF
TLCCRALGFEARYVWDYTDHVWTEVYSPSQQRWLHCDACEDVCDKPLLYE
IGWGKKLSYIIAFSKDEVVDVTWRYSCKHDEVMSRRTKVKEELLRETING
LNKQRQLSLSESRRKELLQRIIVELVEFISPKTPHHHHHH
3D structure
PDB2f4o Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
ChainA
Resolution2.26 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.52: peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N274 R291 N293 R305 C306 G307 D332 N111 R128 N130 R142 C143 G144 D169
BS02 ZN A C247 C250 C280 C283 C306 C84 C87 C117 C120 C143
BS03 ZN A H454 H455 H457 H286 H287 H289
External links
PDB RCSB:2f4o, PDBe:2f4o, PDBj:2f4o
PDBsum2f4o
PubMed16500903
UniProtQ9JI78|NGLY1_MOUSE Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (Gene Name=Ngly1)

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