Structure of PDB 2ex5 Chain A

Receptor sequence
>2ex5A (length=207) [Search protein sequence]
ILKPGEKLPQDKLEELKKINDAVKKTKNFSKYLIDLRKLFQIDEVQVTSE
SKLFLAGFLEGEASLNISTKKLATSKFGLVVDPEFNVTRHVNGVKVLYLA
LEVFKTGRIRHKSGSNATLVLTIDNRQSLEEKVIPFYEQYVVAFSSPEKV
KRVANFKALLELFNNDAHQDLEQLVNKILPIWDQMRKQQGQSNEGFPNLE
AAQDFAR
3D structure
PDB2ex5 The structure of I-CeuI homing endonuclease: Evolving asymmetric DNA recognition from a symmetric protein scaffold.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K21 K28 R114 S117 D128 R130 H172 Q195 S196 N197 K17 K24 R110 S113 D124 R126 H168 Q191 S192 N193
BS02 dna A E66 S68 N70 S72 T73 K74 E88 N90 T92 R93 H94 K116 K191 Q192 N197 E198 E62 S64 N66 S68 T69 K70 E84 N86 T88 R89 H90 K112 K187 Q188 N193 E194
BS03 CA A G65 E66 G61 E62
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006314 intron homing
Cellular Component
GO:0005739 mitochondrion
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ex5, PDBe:2ex5, PDBj:2ex5
PDBsum2ex5
PubMed16698548
UniProtP32761|DNE1_CHLMO DNA endonuclease I-CeuI

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