Structure of PDB 2ewk Chain A

Receptor sequence

>2ewkA (length=107) Species: 883 (Nitratidesulfovibrio vulgaris str. 'Miyazaki F')

APKAPADGLKMDKTKQPVVFNHSVHKAVKCGDCHHPVNGKEDYQKCATAG
CHDNMDKKDKSAKGYYHAMHDKGTKFKSCVGCHLETAGADAAKKKELTGC
KGSKCHS

3D structure

• PDB: 2ewk Strategic roles of axial histidines in structure formation and redox regulation of tetraheme cytochrome c3.
• Chain: A
• Resolution: 1.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	M11 D12 K13 T14 Q16 V18 Y65 Y66 H70 V80 H83 T98 G99 C100 C105 H106	M11 D12 K13 T14 Q16 V18 Y65 Y66 H70 V80 H83 T98 G99 C100 C105 H106
BS02	HEM	A	H35 D42 Q44 C46 C51 H52 H67 A68 T74 K75 F76	H35 D42 Q44 C46 C51 H52 H67 A68 T74 K75 F76
BS03	HEM	A	P2 K3 P5 L9 M11 F20 H22 V28 C30 C33 H34 Y43 K45 C46	P2 K3 P5 L9 M11 F20 H22 V28 C30 C33 H34 Y43 K45 C46
BS04	HEM	A	F20 N21 V24 H25 V28 C79 C82 H83 K93 K104	F20 N21 V24 H25 V28 C79 C82 H83 K93 K104

Gene Ontology

Molecular Function

• GO:0009055 electron transfer activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0009061 anaerobic respiration

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:2ewk, PDBe:2ewk, PDBj:2ewk
• PDBsum: 2ewk
• PubMed: 18702516
• UniProt: P00132|CYC3_NITV9 Cytochrome c3 (Gene Name=DvMF_2499)