Structure of PDB 2ev4 Chain A

Receptor sequence
>2ev4A (length=186) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
ANIDDLLGDLGGTARAERAKLVEWLLEQGITPDEIRATNPPLLLATRHLV
GDDGTYVSAREISENYGVDLELLQRVQRAVGLARVDDPDAVVHMRADGEA
AARAQRFVELGLNPDQVVLVVRVLAEGLSHAAEAMRYTALEAIMRPGATE
LDIAKGSQALVSQIVPLLGPMIQDMLFMQLRHMMET
3D structure
PDB2ev4 The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid
ChainA
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.1: adenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OLA A A114 F117 V127 V130 V131 M194 A104 F107 V117 V120 V121 M184
BS02 OLA A L53 T56 R57 M145 R146 M181 L43 T46 R47 M135 R136 M171
External links
PDB RCSB:2ev4, PDBe:2ev4, PDBj:2ev4
PDBsum2ev4
PubMed17482646
UniProtP9WMU9|Y1264_MYCTU pH-sensitive adenylate cyclase Rv1264 (Gene Name=Rv1264)

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