Structure of PDB 2ev3 Chain A

Receptor sequence
>2ev3A (length=184) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
NIDDLLGDLGGTARAERAKLVEWLLEQGITPDEIRATNPPLLLATRHLVG
DDGTYVSAREISENYGVDLELLQRVQRAVGLARVDDPDAVVHMRADGEAA
ARAQRFVELGLNPDQVVLVVRVLAEGLSHAAEAMRYTALEAIMRPGATEL
DIAKGSQALVSQIVPLLGPMIQDMLFMQLRHMME
3D structure
PDB2ev3 The structure of the regulatory domain of the adenylyl cyclase Rv1264 from Mycobacterium tuberculosis with bound oleic acid
ChainA
Resolution2.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.1: adenylate cyclase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 OLA A A114 F117 V131 M193 M194 A103 F106 V120 M182 M183
BS02 OLA A L53 M145 R146 L178 M181 L42 M134 R135 L167 M170
External links
PDB RCSB:2ev3, PDBe:2ev3, PDBj:2ev3
PDBsum2ev3
PubMed17482646
UniProtP9WMU9|Y1264_MYCTU pH-sensitive adenylate cyclase Rv1264 (Gene Name=Rv1264)

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