Structure of PDB 2el0 Chain A

Receptor sequence
>2el0A (length=265) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
MVLYFIGLGLYDERDITVKGMEIAKKCDYVFAEFYTSLMAGTTLGRIQKL
IGKEIRVLSREDVELNFENIVLPLAKENDVAFLTPGDPLVATTHAELRIR
AKRAGVESYVIHAPSIYSAVGITGLHIYKFGKSATVAYPEGNWFPTSYYD
VIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDD
TLVVVLARAGSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYL
VEIAGAPREILRVNV
3D structure
PDB2el0 Structural study of Project ID PH0725 from Pyrococcus horikoshii OT3 (L21M)
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.98: diphthine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A T36 S37 D87 V90 S115 I116 L166 R208 A209 P233 H234 T36 S37 D87 V90 S115 I116 L166 R208 A209 P233 H234
Gene Ontology
Molecular Function
GO:0004164 diphthine synthase activity
GO:0008168 methyltransferase activity
Biological Process
GO:0017183 protein histidyl modification to diphthamide
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2el0, PDBe:2el0, PDBj:2el0
PDBsum2el0
PubMed
UniProtO58456|DPHB_PYRHO Diphthine synthase (Gene Name=dphB)

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