Structure of PDB 2egv Chain A

Receptor sequence
>2egvA (length=229) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRR
EDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLT
FVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSD
LIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILRE
KGFKSVLLEPYTLRTETAVVSIVSILMNF
3D structure
PDB2egv Crystal structure of rRNA methyltransferase with SAM ligand
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A L161 D162 N163 V184 G185 E187 G189 L207 L208 T212 L213 A218 L161 D162 N163 V184 G185 E187 G189 L207 L208 T212 L213 A218
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0070042 rRNA (uridine-N3-)-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2egv, PDBe:2egv, PDBj:2egv
PDBsum2egv
PubMed
UniProtO66552|RSME_AQUAE Ribosomal RNA small subunit methyltransferase E (Gene Name=rsmE)

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