Structure of PDB 2efy Chain A

Receptor sequence
>2efyA (length=302) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MRVEGAIGKTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKD
AEERGILRPGSGQVIVEPTSGNTGIGLAMIAASRGYRLILTMPAQMSEER
KRVLKAFGAELVLTDPERRMLAAREEALRLKEELGAFMPDQFKNPANVRA
HYETTGPELYEALEGRIDAFVYGSGTGGTITGVGRYLKERIPHVKVIAVE
PARSNVLSGGKMGQHGFQGMGPGFIPENLDLSLLDGVIQVWEEDAFPLAR
RLAREEGLFLGMSSGGIVWAALQVARELGPGKRVACISPDGGWKYLSTPL
YA
3D structure
PDB2efy Crystal Structure of T.th. HB8 O-acetylserine sulfhydrylase Complexed with 4-Acetylbutyric acid
ChainA
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K40 S70 E200 S204 S263
Catalytic site (residue number reindexed from 1) K40 S70 E200 S204 S263
Enzyme Commision number 2.5.1.47: cysteine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A K40 N72 Y172 G175 T176 G177 T179 G219 S263 P289 D290 K40 N72 Y172 G175 T176 G177 T179 G219 S263 P289 D290
BS02 4AT A T69 G71 T73 Q141 G175 G219 M220 P222 T69 G71 T73 Q141 G175 G219 M220 P222
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0080146 L-cysteine desulfhydrase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2efy, PDBe:2efy, PDBj:2efy
PDBsum2efy
PubMed
UniProtQ5SLE6

[Back to BioLiP]