Structure of PDB 2e22 Chain A

Receptor sequence
>2e22A (length=752) Species: 84635 (Bacillus sp. GL1) [Search protein sequence]
SDEFDALRIKWATLLTGGPALDPADSDIAARTDKLAQDANDYWEDMDLSS
SRTYIWYALRGNGTSDNVNAVYERLRTMALAATTVGSSLYGNADLKEDIL
DALDWLYVNSYNSTRSRSAYNWWHWQLGIPMSLNDIAVLLYDDISAARMA
TYMDTIDYFTPSIGLTGANRAWQAIVVGVRAVIVKDAVKLAAARNGLSGT
GIFPYATGGDGFYADGSFVQHTTFAYTGGYGSSVLETTANLMYLLSGSTW
SVSDPNQSNVWQWIYEAYRPLLYKGAMMDMVRGREISRSYAQDHAVGHGI
VASIVRLAQFAPAPHAAAFKQIAKRVIQEDTFSSFYGDVSTDTIRLAKAI
VDDPSIAPAAAPNLYKQYAAMDRAVLQRPGFALGLALYSTRISSYESINS
ENGRGWYTGAGATYLYNQDLAQYSEDYWPTVDAYRIPGTTVASGTPIASG
TGTSSWTGGVSLAGQYGASGMDLSYGAYNLSARKSWFMFDDEIVALGSGI
SSTAGIPIETVVDNRKLNGAGDNAWTANGAALSTGLGVAQTLTGVNWVHL
AGNTADGSDIGYYFPGGATLQTKREARTGTWKQINNRPATPSTAVTRNYE
TMWIDHGTNPSGASYGYVLLPNKTSAQVGAYAADPAIEIVVNTSGVQSVK
EKTLGLVGANFWTDTTQTADLITSNKKASVMTREIADERLEASVSDPTQA
NNGTIAIELARSAEGYSADPGITVTQLAPTIKFTVNVNGAKGKSFHASFQ
LG
3D structure
PDB2e22 A Structural Factor Responsible for Substrate Recognition by Bacillus sp. GL1 Xanthan Lyase that Acts Specifically on Pyruvated Side Chains of Xanthan
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N194 H246 Y255 R309 E421
Catalytic site (residue number reindexed from 1) N169 H221 Y230 R284 E396
Enzyme Commision number 4.2.2.12: xanthan lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN A W148 Y255 R309 R313 W123 Y230 R284 R288 MOAD: Ki=837mM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2e22, PDBe:2e22, PDBj:2e22
PDBsum2e22
PubMed17223699
UniProtQ9AQS0|XANLY_BACGL Xanthan lyase (Gene Name=xly)

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