Structure of PDB 2dxf Chain A

Receptor sequence
>2dxfA (length=153) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
ETERTLVIIKPDAVVRGLIGEIISRFEKKGLKIVGMKMIWIDRELAEKHY
EEHREKPFFKALIDYITKTPVVVMVLEGRYAVEVVRKMAGATDPKDAAPG
TIRGDFGLEVSDAICNVIHASDSKESAEREISLFFKPEELFEYPRAADWF
YKK
3D structure
PDB2dxf Crystal structure of nucleoside diphosphate kinase in complex with GTP analog
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K15 Y55 N121 H124 E135
Catalytic site (residue number reindexed from 1) K10 Y50 N116 H119 E130
Enzyme Commision number 2.7.4.6: nucleoside-diphosphate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A H58 F63 L67 I119 N121 H53 F58 L62 I114 N116
Gene Ontology
Molecular Function
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0046872 metal ion binding
Biological Process
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0009117 nucleotide metabolic process
GO:0009142 nucleoside triphosphate biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2dxf, PDBe:2dxf, PDBj:2dxf
PDBsum2dxf
PubMed
UniProtO58429|NDK_PYRHO Nucleoside diphosphate kinase (Gene Name=ndk)

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