Structure of PDB 2dwa Chain A

Receptor sequence
>2dwaA (length=341) Species: 9913 (Bos taurus) [Search protein sequence]
YTRVVWCAVGPEEQKKCQQWSQQSGQNVTCATASTTDDCIVLVLKGEADA
LNLDGGYIYTAGKCGLVPVLAENRKSSKHSSLDCVLRPTEGYLAVAVVKK
ANEGLTWNSLKDKKSCHTAVDRTAGWNIPMGLIVNQTGSCAFDEFFSQSC
APGADPKSRLCALCAGDDQGLDKCVPNSKEKYYGYTGAFRCLAEDVGDVA
FVKNDTVWENTNGESTADWAKNLKREDFRLLCLDGTRKPVTEAQSCHLAV
APNHAVVSRSDRAAHVEQVLLHQQALFGKNGKNCPDKFCLFKSETKNLLF
NDNTECLAKLGGRPTYEEYLGTEYVTAIANLKKCSLEACAF
3D structure
PDB2dwa Structure of the complex of lactoferrin C-terminal half with fucose at 2.07 A resolution
ChainA
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FUC A T430 E431 G432 A592 P593 Y660 T89 E90 G91 A251 P252 Y319
BS02 FE A D395 Y433 Y526 H595 D54 Y92 Y185 H254
BS03 CO3 A D395 T459 R463 T464 A465 Y526 D54 T118 R122 T123 A124 Y185
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:2dwa, PDBe:2dwa, PDBj:2dwa
PDBsum2dwa
PubMed
UniProtP24627|TRFL_BOVIN Lactotransferrin (Gene Name=LTF)

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