Structure of PDB 2dvq Chain A

Receptor sequence
>2dvqA (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
GRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMD
MGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKI
FLQKVASMPQEEQE
3D structure
PDB2dvq Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain.
ChainA
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D112 I116 Y155 N156 D160 I162 D40 I44 Y83 N84 D88 I90
BS02 peptide A Y153 I154 K157 P158 T159 Q167 Y81 I82 K85 P86 T87 Q95
External links
PDB RCSB:2dvq, PDBe:2dvq, PDBj:2dvq
PDBsum2dvq
PubMed20048151
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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