Structure of PDB 2dvn Chain A

Receptor sequence
>2dvnA (length=186) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence]
MKIFFITSNPGKVREVANFLGTFGIEIVQLKHEYPEIQAEKLEDVVDFGI
SWLKGKVPEPFMIEDSGLFIESLKGFPGVYSSYVYRTIGLEGILKLMEGA
EDRRAYFKSVIGFYIDGKAYKFSGVTWGRISNEKRGTHGFGYDPIFIPEG
SEKTFAEMTIEEKNALSHRGKALKAFFEWLKVNLKY
3D structure
PDB2dvn Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.66: XTP/dITP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP A D65 S66 S81 S82 F107 F140 G141 Y142 D143 K163 H168 R169 D65 S66 S81 S82 F107 F140 G141 Y142 D143 K163 H168 R169
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0035870 dITP diphosphatase activity
GO:0036220 ITP diphosphatase activity
GO:0036222 XTP diphosphatase activity
GO:0046872 metal ion binding
GO:0047429 nucleoside triphosphate diphosphatase activity
Biological Process
GO:0009117 nucleotide metabolic process
GO:0009143 nucleoside triphosphate catabolic process
GO:0009146 purine nucleoside triphosphate catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2dvn, PDBe:2dvn, PDBj:2dvn
PDBsum2dvn
PubMed18062990
UniProtO59580|IXTPA_PYRHO dITP/XTP pyrophosphatase (Gene Name=PH1917)

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