Structure of PDB 2df3 Chain A

Receptor sequence
>2df3A (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
KDYSLTMQSSVTVQEGMCVHVRCSFSYPVTDSDPVHGYWFRASWKAPVAT
NNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNI
KWNYKYDQLSVNVT
3D structure
PDB2df3 The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
ChainA
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA A R124 K131 W132 N133 R94 K101 W102 N103
BS02 CYS A C41 V42 H43 C18 V19 H20
External links
PDB RCSB:2df3, PDBe:2df3, PDBj:2df3
PDBsum2df3
PubMed16623661
UniProtQ9Y286|SIGL7_HUMAN Sialic acid-binding Ig-like lectin 7 (Gene Name=SIGLEC7)

[Back to BioLiP]