Structure of PDB 2d7i Chain A

Receptor sequence
>2d7iA (length=536) Species: 9606 (Homo sapiens) [Search protein sequence]
GQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMTDAERVDQAYRENGFNIYV
SDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHS
VLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMALFPSVRILRTKKREGL
IRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMID
VIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVM
AGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSR
VGHIYRKYVPYKVPAGVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSA
GDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYPPVEPPAAAWGEIRNVG
TGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQ
HTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDKTLYHPVSGSCMDCS
ESDHRIFMNTCNPSSLTQQWLFEHTNSTVLEKFNRN
3D structure
PDB2d7i Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10)
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.41: polypeptide N-acetylgalactosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D237 H239 H370 D170 H172 H303
BS02 UDP A F153 H154 E156 D185 R214 G216 L217 D237 S238 H239 W342 H370 R373 Y378 F86 H87 E89 D118 R147 G149 L150 D170 S171 H172 W275 H303 R306 Y311
Gene Ontology
Molecular Function
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
Biological Process
GO:0006486 protein glycosylation
GO:0006493 protein O-linked glycosylation
GO:0016266 O-glycan processing
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2d7i, PDBe:2d7i, PDBj:2d7i
PDBsum2d7i
PubMed16650853
UniProtQ86SR1|GLT10_HUMAN Polypeptide N-acetylgalactosaminyltransferase 10 (Gene Name=GALNT10)

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