Structure of PDB 2d5x Chain A

Receptor sequence
>2d5xA (length=141) Species: 9796 (Equus caballus) [Search protein sequence]
VLSAADKTNVKAAWSKVGGHAGEYGAEALERMFLGFPTTKTYFPHFDLSH
GSAQVKAHGKKVGDALTLAVGHLDDLPGALSNLSDLHAHKLRVDPVNFKL
LSHCLLSTLAVHLPNDFTPAVHASLDKFLSSVSTVLTSKYR
3D structure
PDB2d5x R-state haemoglobin with low oxygen affinity: crystal structures of deoxy human and carbonmonoxy horse haemoglobin bound to the effector molecule L35
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A Y42 F43 H58 K61 L83 H87 L91 V93 N97 F98 L101 L136 Y42 F43 H58 K61 L83 H87 L91 V93 N97 F98 L101 L136
BS02 L35 A N82 L83 L86 K90 N82 L83 L86 K90
BS03 L35 A K99 L100 H103 K99 L100 H103
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0005344 oxygen carrier activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0031720 haptoglobin binding
GO:0043177 organic acid binding
GO:0046872 metal ion binding
Biological Process
GO:0015671 oxygen transport
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005833 hemoglobin complex
GO:0031838 haptoglobin-hemoglobin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2d5x, PDBe:2d5x, PDBj:2d5x
PDBsum2d5x
PubMed16403522
UniProtP01958|HBA_HORSE Hemoglobin subunit alpha (Gene Name=HBA)

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