Structure of PDB 2d1x Chain A
Receptor sequence
>2d1xA (length=60) Species:
9606
(Homo sapiens) [
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NDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGL
FPANYVELRQ
3D structure
PDB
2d1x
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Chain
A
Resolution
1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
A
Y12 E21 W40 N55 Y56
Y11 E20 W39 N54 Y55
External links
PDB
RCSB:2d1x
,
PDBe:2d1x
,
PDBj:2d1x
PDBsum
2d1x
PubMed
16636290
UniProt
Q14247
|SRC8_HUMAN Src substrate cortactin (Gene Name=CTTN)
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