Structure of PDB 2d0b Chain A

Receptor sequence
>2d0bA (length=308) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
SNYVIQADQQLLDALRAHYEGALSDRLPAGALFAVKRPDVVITAYRSGKV
LFQGKAAEQEAAKWISGASASNETADHQPSALAAHQLGSLSAIGSDEVGT
GDYFGPIVVAAAYVDRPHIAKIAALGVKDSKQLNDEAIKRIAPAIMETVP
HAVTVLDNPQYNRWQRSGMPQTKMKALLHNRTLVKLVDAIAPAEPEAIII
DEFLKRDSYFRYLSDEDRIIRERVHCLPKAESVHVSVAAASIIARYVFLE
EMEQLSRAVGLLLPKGAGAIVDEAAARIIRARGEEMLETCAKLHFANTKK
ALAIAKRR
3D structure
PDB2d0b Crystal structure and structure-based mutational analyses of RNase HIII from Bacillus stearothermophilus: a new type 2 RNase H with TBP-like substrate-binding domain at the N terminus
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D97 E98 D202 D96 E97 D201
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006298 mismatch repair
GO:0006401 RNA catabolic process
GO:0016070 RNA metabolic process
GO:0043137 DNA replication, removal of RNA primer
Cellular Component
GO:0005737 cytoplasm
GO:0032299 ribonuclease H2 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2d0b, PDBe:2d0b, PDBj:2d0b
PDBsum2d0b
PubMed16343535
UniProtQ6L6Q4

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