Structure of PDB 2cz2 Chain A

Receptor sequence
>2cz2A (length=212) Species: 10090 (Mus musculus) [Search protein sequence]
GKPILYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTL
NPMKQVPALKIDGITIVQSLAIMEYLEETRPIPRLLPQDPQKRAIVRMIS
DLIASGIQPLQNLSVLKQVGQENQMQWAQKVITSGFNALEKILQSTAGKY
CVGDEVSMADVCLVPQVANAERFKVDLSPYPTISHINKELLALEVFQVSH
PRRQPDTPAELR
3D structure
PDB2cz2 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from Mus musculus (form-1 crystal)
ChainA
Resolution1.4 Å
3D
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Enzymatic activity
Enzyme Commision number 2.5.1.18: glutathione transferase.
5.2.1.2: maleylacetoacetate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A S14 C16 L38 Q45 Q58 V59 Q71 S72 Q111 N115 S117 S11 C13 L35 Q42 Q55 V56 Q68 S69 Q108 N112 S114
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004364 glutathione transferase activity
GO:0016034 maleylacetoacetate isomerase activity
GO:0016740 transferase activity
GO:0016853 isomerase activity
Biological Process
GO:0006559 L-phenylalanine catabolic process
GO:0006572 tyrosine catabolic process
GO:0009072 aromatic amino acid metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Cellular Component
External links
PDB RCSB:2cz2, PDBe:2cz2, PDBj:2cz2
PDBsum2cz2
PubMed
UniProtQ9WVL0|MAAI_MOUSE Maleylacetoacetate isomerase (Gene Name=Gstz1)

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