Structure of PDB 2cyc Chain A

Receptor sequence
>2cycA (length=371) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
MDIEERINLVLKKPTEEVLTVENLRHLFEIGAPLQHYIGFEISGYIHLGT
GLMAGAKIADFQKAGIKTRVFLADWHSWINDKLGGDLEVIQEVALKYFKV
GMEKSIEVMGGDPKKVEFVLASEILEKGDYWQTVIDISKNVTLSRVMRSI
TIMGRQMGEAIDFAKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVIAIEV
AQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIESEEEFKEIKAQM
KMSKSKPYSAVFIHDSPEEIRQKLRKAFCPAREVRYNPVLDWVEYIIFRE
EPTEFTVHRPAKFGGDVTYTTFEELKRDFAEGKLHPLDLKNAVAEYLINL
LEPIRRYFEKHPEPLELMRSV
3D structure
PDB2cyc Crystal Structures of Tyrosyl-tRNA Synthetases from Archaea
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.1: tyrosine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYR A Y37 G39 H76 Y168 Q172 D175 Q190 Y37 G39 H76 Y168 Q172 D175 Q190
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004831 tyrosine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006437 tyrosyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2cyc, PDBe:2cyc, PDBj:2cyc
PDBsum2cyc
PubMed16325203
UniProtO58739|SYY_PYRHO Tyrosine--tRNA ligase (Gene Name=tyrS)

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