Structure of PDB 2cx8 Chain A

Receptor sequence
>2cx8A (length=225) Species: 274 (Thermus thermophilus) [Search protein sequence]
HRAFSPGLTGVLPLRETRHLVEVLRARVGDRFTVFDGEREALAEVVDLGP
PLRYRVLEERRPEREVGVEVVLYVALLKGDKLAEVVRAATELGATRIQPL
VTRHSVPKEMGEGKLRRLRAVALEAAKQSGRVVVPEVLPPIPLKAVPQVA
QGLVAHVGATARVREVLDPEKPLALAVGPEGGFAEEEVALLEARGFTPVS
LGRRILRAETAALALLALCTAGEGR
3D structure
PDB2cx8 Crystal structure of methyltransferase with ligand(SAH)
ChainA
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A A158 H159 V160 V180 G181 P182 E183 G185 L204 L209 A214 A155 H156 V157 V177 G178 P179 E180 G182 L201 L206 A211
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0070042 rRNA (uridine-N3-)-methyltransferase activity
Biological Process
GO:0006364 rRNA processing
GO:0032259 methylation
GO:0070475 rRNA base methylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cx8, PDBe:2cx8, PDBj:2cx8
PDBsum2cx8
PubMed
UniProtQ5SKI6

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