Structure of PDB 2ckp Chain A

Receptor sequence
>2ckpA (length=316) Species: 9606 (Homo sapiens) [Search protein sequence]
RTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPPRKVL
LRLYAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSL
PDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLSRIKKLHKLL
SYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILMLIDFEYSSYNYRGF
DIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFE
NLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYA
QARFDAYFHQKRKLGV
3D structure
PDB2ckp Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine.
ChainA
Resolution3.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.1.32: choline kinase.
2.7.1.82: ethanolamine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R117 N122 L124 R146 Q207 F208 I209 S211 R212 R213 D330 R32 N37 L39 R52 Q86 F87 I88 S90 R91 R92 D189
External links
PDB RCSB:2ckp, PDBe:2ckp, PDBj:2ckp
PDBsum2ckp
PubMed17007874
UniProtP35790|CHKA_HUMAN Choline kinase alpha (Gene Name=CHKA)

[Back to BioLiP]