Structure of PDB 2cjw Chain A

Receptor sequence
>2cjwA (length=178) Species: 9606 (Homo sapiens) [Search protein sequence]
MTYYRVVLIGEQGVGKSTLANIFAGVHDSCEVLGEDTYERTLMVDGESAT
IILLDMWENEWLHDHCMQVGDAYLIVYSITDRASFEKASELRIQLRRARQ
TEDIPIILVGNKSDLVRCREVSVSEGRACAVVFDCKFIETSAAVQHNVKE
LFEGIVRQVRLRRDSKEKNERRLAYQKR
3D structure
PDB2cjw Biochemical and Structural Characterization of the Gem Gtpase.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A G85 G87 K88 S89 T90 N191 K192 D194 L195 S221 A223 G13 G15 K16 S17 T18 N111 K112 D114 L115 S141 A143 MOAD: Kd=2.5uM
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:2cjw, PDBe:2cjw, PDBj:2cjw
PDBsum2cjw
PubMed17107948
UniProtP55040|GEM_HUMAN GTP-binding protein GEM (Gene Name=GEM)

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