Structure of PDB 2cic Chain A

Receptor sequence
>2cicA (length=223) Species: 197 (Campylobacter jejuni) [Search protein sequence]
MTNIEILENMLKLQQKLNDETNGLNWENGYTKEGKLISWRRCIYMECAEL
IDSFTWKHWKNISSLTNWENVRIEIVDIWHFILSLLLEEYDFKAIATEVN
AVSVFQDFCKEEEYPNEGDIYGILNDIELIIHKCSGFGFNLGELLSTYFT
LAIKCGLNLEILYKTYIGKNVLNIFRQNNGYKDGSYKKTWNGKEDNEVLA
QILEQELDFDTIYKKLEECYKKA
3D structure
PDB2cic The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.
ChainA
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUP A Q14 N18 W39 D77 H80 F81 K175 N179 R182 Y187 K194 N202 Q14 N18 W39 D77 H80 F81 K169 N173 R176 Y181 K188 N196
BS02 MG A E46 E74 D77 E46 E74 D77
Gene Ontology
Molecular Function
GO:0004170 dUTP diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2cic, PDBe:2cic, PDBj:2cic
PDBsum2cic
PubMed21454646
UniProtQ0P8G4

[Back to BioLiP]