Structure of PDB 2cg9 Chain A

Receptor sequence
>2cg9A (length=609) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
ASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLS
DPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGT
KAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESN
AGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFV
AYPIQLVVTKEVEKEEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSI
SNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFNNIKLYVRRVFITDEAE
DLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFN
EIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELT
SLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPI
DEYAFTQLKEFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALK
EILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQAKTFEISPK
SPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRI
NRLISLGLN
3D structure
PDB2cg9 Crystal Structure of an Hsp90-Nucleotide-P23/Sba1 Closed Chaperone Complex
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A N37 A41 D79 M84 N92 S99 G100 G118 Q119 G121 V122 G123 F124 R380 N36 A40 D78 M83 N91 S98 G99 G117 Q118 G120 V121 G122 F123 R325
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0000492 box C/D snoRNP assembly
GO:0006457 protein folding
GO:0006458 'de novo' protein folding
GO:0006626 protein targeting to mitochondrion
GO:0006970 response to osmotic stress
GO:0032204 regulation of telomere maintenance
GO:0032212 positive regulation of telomere maintenance via telomerase
GO:0034605 cellular response to heat
GO:0042026 protein refolding
GO:0043248 proteasome assembly
GO:0050821 protein stabilization
GO:0051604 protein maturation
GO:0070482 response to oxygen levels
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0032991 protein-containing complex
GO:0048471 perinuclear region of cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2cg9, PDBe:2cg9, PDBj:2cg9
PDBsum2cg9
PubMed16625188
UniProtP02829|HSP82_YEAST ATP-dependent molecular chaperone HSP82 (Gene Name=HSP82)

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