Structure of PDB 2c3e Chain A

Receptor sequence
>2c3eA (length=293) Species: 9913 (Bos taurus) [Search protein sequence]
SDQALSFLKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQISAEKQY
KGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG
GVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQ
REFTGLGNCITKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGM
LPDPKNVHIIVSWMIAQTVTAVAGLVSYPFDTVRRRMMMQSGRKGADIMY
TGTVDCWRKIAKDEGPKAFFKGAWSNVLRGMGGAFVLVLYDEI
3D structure
PDB2c3e Structural Basis for Lipid-Mediated Interactions between Mitochondrial Adp/ATP Carrier Monomers.
ChainA
Resolution2.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0005471 ATP:ADP antiporter activity
GO:0015297 antiporter activity
GO:0017077 oxidative phosphorylation uncoupler activity
Biological Process
GO:0015866 ADP transport
GO:0046902 regulation of mitochondrial membrane permeability
GO:0055085 transmembrane transport
GO:0140021 mitochondrial ADP transmembrane transport
GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1901526 positive regulation of mitophagy
GO:1902600 proton transmembrane transport
GO:1990544 mitochondrial ATP transmembrane transport
GO:1990845 adaptive thermogenesis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005757 mitochondrial permeability transition pore complex
GO:0031966 mitochondrial membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:2c3e, PDBe:2c3e, PDBj:2c3e
PDBsum2c3e
PubMed16226253
UniProtP02722|ADT1_BOVIN ADP/ATP translocase 1 (Gene Name=SLC25A4)

[Back to BioLiP]