Structure of PDB 2bz0 Chain A

Receptor sequence
>2bz0A (length=168) Species: 562 (Escherichia coli) [Search protein sequence]
MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARV
HSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLN
KIRAYALQDQGYDTVEGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKV
EILTEAGINIVERVPLIV
3D structure
PDB2bz0 GTP Cyclohydrolase II Structure and Mechanism.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.25: GTP cyclohydrolase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C54 C65 C67 C54 C65 C67
BS02 MG A H51 S52 H51 S52
BS03 G2P A R49 S52 G93 R94 T114 R128 T149 K154 R49 S52 G93 R94 T114 R123 T144 K149
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0003935 GTP cyclohydrolase II activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2bz0, PDBe:2bz0, PDBj:2bz0
PDBsum2bz0
PubMed16115872
UniProtP0A7I7|RIBA_ECOLI GTP cyclohydrolase-2 (Gene Name=ribA)

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