Structure of PDB 2bpc Chain A

Receptor sequence
>2bpcA (length=242) Species: 10116 (Rattus norvegicus) [Search protein sequence]
DDTSSSINFLTRVTGIGPSAARKLVDEGIKTLEDLRKNEDKLNHHQRIGL
KYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGSFRRGAESSGD
MDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTI
NEYTIRPLGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
3D structure
PDB2bpc Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism.
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D190 D192 D256
Catalytic site (residue number reindexed from 1) D100 D102 D163
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
4.2.99.-
4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D190 D256 D100 D163
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034061 DNA polymerase activity
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2bpc, PDBe:2bpc, PDBj:2bpc
PDBsum2bpc
PubMed7516581
UniProtP06766|DPOLB_RAT DNA polymerase beta (Gene Name=Polb)

[Back to BioLiP]