Structure of PDB 2bio Chain A

Receptor sequence
>2bioA (length=186) Species: 9606 (Homo sapiens) [Search protein sequence]
VPSQKTYQGSYGFRLGFLHSSVTCTYSPALNKLFCQLAKTCPVQLWVDST
PPPGTRVRAMAIYKQSQHMTEVVRRCPHHERDGLAPPQHLIRVEGNLRAE
YLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCYSSCMGGMNRSPILTI
ITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENLR
3D structure
PDB2bio Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C176 H179 C242 C76 H79 C138
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2bio, PDBe:2bio, PDBj:2bio
PDBsum2bio
PubMed15703170
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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