Structure of PDB 2bgw Chain A

Receptor sequence
>2bgwA (length=219) Species: 56636 (Aeropyrum pernix) [Search protein sequence]
MLEDPGGRPRVYVDVREERSPVPSILESLGVQVIPKQLPMGDYLVSDSII
VERKTSSDFAKSLFDGRLFEQASRLAEHYETVFIIVEGPPVPRRYRGRER
SLYAAMAALQLDYGIRLMNTMDPKGTALVIESLARLSTREGGQRIVIHKK
PRLSDVREWQLYILQSFPGIGRRTAERILERFGSLERFFTASKAEISKVE
GIGEKRAEEIKKILMTPYK
3D structure
PDB2bgw Structure of an XPF endonuclease with and without DNA suggests a model for substrate recognition.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A A86 Y123 G179 I180 G181 R182 R183 T184 R187 A76 Y113 G169 I170 G171 R172 R173 T174 R177
BS02 dna A D122 Y123 G124 E210 G211 G213 R216 D112 Y113 G114 E200 G201 G203 R206
BS03 MG A D52 E62 R63 D42 E52 R53
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004518 nuclease activity
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2bgw, PDBe:2bgw, PDBj:2bgw
PDBsum2bgw
PubMed15719018
UniProtQ9YC15

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