Structure of PDB 2bbu Chain A

Receptor sequence
>2bbuA (length=156) Species: 10090 (Mus musculus) [Search protein sequence]
EYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHF
FTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMP
PPGTPSFSLPPTEPSSEVPEQPPAQALPGSTPKRAYYIYSGGEKIPLVLS
RPLSSN
3D structure
PDB2bbu The Structure of SOCS3 Reveals the Basis of the Extended SH2 Domain Function and Identifies an Unstructured Insertion That Regulates Stability
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A G24 K62 N63 L64 R65 Q76 H97 A135 Y136 Y137 Y139 G24 K62 N63 L64 R65 Q76 H97 A135 Y136 Y137 Y139
External links
PDB RCSB:2bbu, PDBe:2bbu, PDBj:2bbu
PDBsum2bbu
PubMed16630890
UniProtO35718|SOCS3_MOUSE Suppressor of cytokine signaling 3 (Gene Name=Socs3)

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