Structure of PDB 2bbr Chain A

Receptor sequence
>2bbrA (length=189) Species: 10280 (Molluscum contagiosum virus subtype 1) [Search protein sequence]
SDSKEVPSLPFLRHLLEELDSHEDSLLLFLCHDAAPGCTTVTQALCSLSQ
QRKLTLAALVEMLYVLQRMDLLKSRFGLSKEGAEQLLGTSFLTRYRKLMV
CVGEELDSSELRALRLFACNLNPSLSTALSESSRFVELVLALENVGLVSP
SSVSVLADMLRTLRRLDLCQQLVEYEQQEQARYRYCLHH
3D structure
PDB2bbr Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AZI A L88 R95 K98 L87 R94 K97
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2bbr, PDBe:2bbr, PDBj:2bbr
PDBsum2bbr
PubMed16364918
UniProtQ98325|CFLA_MCV1 Viral CASP8 and FADD-like apoptosis regulator (Gene Name=MC159L)

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