Structure of PDB 2bba Chain A

Receptor sequence
>2bbaA (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
HHHHHEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVC
DVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETF
TVFYYESDADTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNV
KTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKK
3D structure
PDB2bba Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E43 L45 G47 E59 C61 T93 L95 P101 K149 A155 G157 M185 E32 L34 G36 E48 C50 T82 L84 P90 K138 A144 G146 M174
External links
PDB RCSB:2bba, PDBe:2bba, PDBj:2bba
PDBsum2bba
PubMed16472751
UniProtP54760|EPHB4_HUMAN Ephrin type-B receptor 4 (Gene Name=EPHB4)

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