Structure of PDB 2b8j Chain A

Receptor sequence
>2b8jA (length=211) Species: 562 (Escherichia coli) [Search protein sequence]
SPSPLNPGTNVARLAEQAPIHWVSVAQIENSLAGRPPMAVGFDIDDTVLF
SSPGFWRGKKTFSPESEDYLKNPVFWEKMNNGWDEFSIPKEVARQLIDMH
VRRGDAIFFVTGRSPTKTETVSKTLADNFHIPATNMNPVIFAGDKPGQNT
KSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTYKPLPQAGA
FGEEVIVNSEY
3D structure
PDB2b8j A structure-based proposal for the catalytic mechanism of the bacterial acid phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases
ChainA
Resolution2.033 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.2: acid phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D44 D46 D167 D43 D45 D166
BS02 PO4 A G113 K152 G112 K151
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003993 acid phosphatase activity
GO:0016787 hydrolase activity
GO:0036424 L-phosphoserine phosphatase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2b8j, PDBe:2b8j, PDBj:2b8j
PDBsum2b8j
PubMed16330049
UniProtP0AE22|APHA_ECOLI Class B acid phosphatase (Gene Name=aphA)

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