Structure of PDB 2b7f Chain A

Receptor sequence
>2b7fA (length=116) Species: 11908 (Human T-cell leukemia virus type I) [Search protein sequence]
PVIPLDPARRPVIKAQVDTQTSHPKTIEALLDTGADMTVIPIALFSSNTP
LKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAI
IGRDALQQCQGVLYLP
3D structure
PDB2b7f Crystal structure of human T cell leukemia virus protease, a novel target for anticancer drug design
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R10 D32 G34 A35 D36 M37 S55 V56 L57 Q62 W98 R10 D32 G34 A35 D36 M37 S55 V56 L57 Q62 W98
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2b7f, PDBe:2b7f, PDBj:2b7f
PDBsum2b7f
PubMed16352712
UniProtP03362|POL_HTL1A Gag-Pro-Pol polyprotein (Gene Name=gag-pro-pol)

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