Structure of PDB 2b4q Chain A

Receptor sequence
>2b4qA (length=256) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
MHPYFSLAGRIALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTA
TRLSAYGDCQAIPADLSSEAGARRLAQALGELSARLDILVNNAGTSWGAA
LESYPVSGWEKVMQLNVTSVFSCIQQLLPLLRRSASAENPARVINIGSVA
GISAMGEQAYAYGPSKAALHQLSRMLAKELVGEHINVNVIAPGRFPSRMT
RHIANDPQALEADSASIPMGRWGRPEEMAALAISLAGTAGAYMTGNVIPI
DGGFHL
3D structure
PDB2b4q Structure of RhlG, an Essential beta-Ketoacyl Reductase in the Rhamnolipid Biosynthetic Pathway of Pseudomonas aeruginosa.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G20 S148 V149 Y162 K166
Catalytic site (residue number reindexed from 1) G20 S148 V149 Y162 K166
Enzyme Commision number 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G16 S18 R19 I21 A40 R41 D42 D65 L66 S67 N92 A93 G94 I146 G147 S148 Y162 K166 P192 G193 R194 F195 S197 M199 G16 S18 R19 I21 A40 R41 D42 D65 L66 S67 N92 A93 G94 I146 G147 S148 Y162 K166 P192 G193 R194 F195 S197 M199
Gene Ontology
Molecular Function
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0008709 cholate 7-alpha-dehydrogenase activity
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:2b4q, PDBe:2b4q, PDBj:2b4q
PDBsum2b4q
PubMed16624803
UniProtQ9RPT1|RHLG_PSEAE Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase (Gene Name=rhlG)

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