Structure of PDB 2b2w Chain A

Receptor sequence
>2b2wA (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
EEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQY
LIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASP
EDVEYYNCQQELTDDLHKQYQIVGRIIAHSNQKSAAGYPDYYCKWQGLPY
SECSWEDGALISKKFQACIDEYFSRKK
3D structure
PDB2b2w Double chromodomains cooperate to recognize the methylated histone H3 tail.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E14 Y37 W64 W67 D150 D167 E4 Y27 W54 W57 D140 D157
External links
PDB RCSB:2b2w, PDBe:2b2w, PDBj:2b2w
PDBsum2b2w
PubMed16372014
UniProtO14646|CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (Gene Name=CHD1)

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