Structure of PDB 2axa Chain A

Receptor sequence
>2axaA (length=238) Species: 9606 (Homo sapiens) [Search protein sequence]
IFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKA
LPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFN
EYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGL
KNQKFFDELRMNYIKELDRIIACSRRFYQLTKLLDSVQPIARELHQFTFD
LLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFH
3D structure
PDB2axa Structural Basis for Accommodation of Nonsteroidal Ligands in the Androgen Receptor
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FHM A L704 N705 Q711 W741 M742 M745 V746 M749 F764 T877 M895 I899 L33 N34 Q40 W70 M71 M74 V75 M78 F93 T198 M216 I220 MOAD: Ki=6.1nM
BindingDB: Ki=6.1nM
External links
PDB RCSB:2axa, PDBe:2axa, PDBj:2axa
PDBsum2axa
PubMed16129672
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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