Structure of PDB 2ate Chain A

Receptor sequence
>2ateA (length=162) Species: 562 (Escherichia coli) [Search protein sequence]
ARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAES
AEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSI
VQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTD
EVLENPDPRGAA
3D structure
PDB2ate N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.4.99.18: 5-(carboxyamino)imidazole ribonucleotide mutase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NIA A G15 S16 D19 S43 A44 H45 R46 A70 G71 G8 S9 D12 S36 A37 H38 R39 A63 G64 PDBbind-CN: -logKd/Ki=7.07,Kd=86nM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016853 isomerase activity
GO:0034023 5-(carboxyamino)imidazole ribonucleotide mutase activity
GO:0042802 identical protein binding
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
Cellular Component
GO:0005829 cytosol

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External links
PDB RCSB:2ate, PDBe:2ate, PDBj:2ate
PDBsum2ate
PubMed17298082
UniProtP0AG18|PURE_ECOLI N5-carboxyaminoimidazole ribonucleotide mutase (Gene Name=purE)

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