Structure of PDB 2ask Chain A

Receptor sequence
>2askA (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
ARGCRLRSQLVPVRALGLGHRSDELVRFRFCSGSCRRARSPHDLSLASLL
GAGALRPPPGSRPVSQPCCRPTRYEAVSFMDVNSTWRTVDRLSATACGCL
G
3D structure
PDB2ask Artemin crystal structure reveals insights into heparan sulfate binding.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SO4 A S46 R48 R49 S34 R36 R37
BS02 SO4 A R14 R48 R2 R36
BS03 SO4 A H32 R33 S34 D93 V94 H20 R21 S22 D81 V82
BS04 SO4 A Q21 L22 R39 Q9 L10 R27
Gene Ontology
Molecular Function
GO:0008083 growth factor activity
GO:0030116 glial cell-derived neurotrophic factor receptor binding
GO:0030971 receptor tyrosine kinase binding

View graph for
Molecular Function
External links
PDB RCSB:2ask, PDBe:2ask, PDBj:2ask
PDBsum2ask
PubMed16734417
UniProtQ5T4W7|ARTN_HUMAN Artemin (Gene Name=ARTN)

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