Structure of PDB 2art Chain A

Receptor sequence
>2artA (length=247) Species: 2303 (Thermoplasma acidophilum) [Search protein sequence]
MEGRLLLLETPGNTRMSLAYDEAIYRSFQYGDKPILRFYRHDRSVIIGYF
QVAEEEVDLDYMKKNGIMLARRYTGGGAVYHDLGDLNFSVVRSSDDMDIT
SMFRTMNEAVVNSLRILGLDARPGELNDVSIPVNKKTDIMAGEKKIMGAA
GAMRKGAKLWHAAMLVHTDLDMLSAVLKVPSTRERVANVTDFVDVSIDEV
RNALIRGFSETLHIDFREDTITEKEESLARELFDKKYSTEEWNMGLL
3D structure
PDB2art Crystal structure of lipoate-protein ligase A bound with the activated intermediate: insights into interaction with lipoyl domains
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.1.20: lipoate--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A T137 D138 G148 A149 T137 D138 G148 A149
BS02 LPA A I46 G77 V79 H81 G148 A149 H161 A162 A163 I46 G77 V79 H81 G148 A149 H161 A162 A163
BS03 AMP A G77 V79 Y80 P132 K135 K145 A163 L165 L173 G77 V79 Y80 P132 K135 K145 A163 L165 L173
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016979 lipoate-protein ligase activity
GO:0017118 lipoyltransferase activity
GO:0031405 lipoic acid binding
GO:0046872 metal ion binding
Biological Process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2art, PDBe:2art, PDBj:2art
PDBsum2art
PubMed16141198
UniProtQ9HKT1|LPLAN_THEAC Lipoate-protein ligase A subunit 1 (Gene Name=lplA)

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