Structure of PDB 2amb Chain A

Receptor sequence
>2ambA (length=246) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACKRTSCSRRFYQLTKLLDSVQPIAREL
HQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ
3D structure
PDB2amb Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 17H A L704 N705 L707 M742 M745 M749 F764 T877 L34 N35 L37 M72 M75 M79 F94 T204
External links
PDB RCSB:2amb, PDBe:2amb, PDBj:2amb
PDBsum2amb
PubMed16641486
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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