Structure of PDB 2ad8 Chain A

Receptor sequence
>2ad8A (length=571) Species: 2327 (Methylophilus methylotrophus W3A1) [Search protein sequence]
DADLDKQVNTAGAWPIATGGYYSQHNSPLAQINKSNVKNVKAAWSFSTGV
LNGHEGAPLVIGDMMYVHSAFPNNTYALNLNDPGKIVWQHKPKQDASTKA
VMCCDVVDRGLAYGAGQIVKKQANGHLLALDAKTGKINWEVEVCDPKVGS
TLTQAPFVAKDTVLMGCSGAELGVRGAVNAFDLKTGELKWRAFATGSDDS
VRLAKDFNSANPHYGQFGLGTKTWEGDAWKIGGGTNWGWYAYDPKLNLFY
YGSGNPAPWNETMRPGDNKWTMTIWGRDLDTGMAKWGYQKTPHDEWDFAG
VNQMVLTDQPVNGKMTPLLSHIDRNGILYTLNRENGNLIVAEKVDPAVNV
FKKVDLKTGTPVRDPEFATRMDHKGTNICPSAMGFHNQGVDSYDPESRTL
YAGLNHICMDWEPFMLPYRAGQFFVGATLAMYPGPNGPTKKEMGQIRAFD
LTTGKAKWTKWEKFAAWGGTLYTKGGLVWYATLDGYLKALDNKDGKELWN
FKMPSGGIGSPMTYSFKGKQYIGSMYGVGGWPGVGLVFDLTDPSAGLGAV
GAFRELQNHTQMGGGLMVFSL
3D structure
PDB2ad8 The enzymatic reaction-induced configuration change of the prosthetic group PQQ of methanol dehydrogenase
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E171 N255 D297
Catalytic site (residue number reindexed from 1) E171 N255 D297
Enzyme Commision number 1.1.2.7: methanol dehydrogenase (cytochrome c).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E171 N255 D297 E171 N255 D297
BS02 PQQ A E55 C103 C104 R109 T153 S168 G169 A170 E171 T235 W237 R324 N387 W467 G530 W531 E55 C103 C104 R109 T153 S168 G169 A170 E171 T235 W237 R324 N387 W467 G530 W531
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0046872 metal ion binding
GO:0052933 alcohol dehydrogenase (cytochrome c(L)) activity
Biological Process
GO:0015945 methanol metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ad8, PDBe:2ad8, PDBj:2ad8
PDBsum2ad8
PubMed21356200
UniProtP38539|DHM1_METME Methanol dehydrogenase [cytochrome c] subunit 1

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