Structure of PDB 2aax Chain A

Receptor sequence
>2aaxA (length=261) Species: 9606 (Homo sapiens) [Search protein sequence]
ALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNR
LAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRSYKH
TNSQFLYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTI
MKVLLLLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKCNNSGQSWQRFY
QLTKLLDSMHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVE
SGNAKPLYFHR
3D structure
PDB2aax A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PDN A L769 N770 A773 Q776 L810 F829 M845 M852 F941 C942 T945 L48 N49 A52 Q55 L89 F108 M124 M131 F219 C220 T223
External links
PDB RCSB:2aax, PDBe:2aax, PDBj:2aax
PDBsum2aax
PubMed15967794
UniProtP08235|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)

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