Structure of PDB 2aa7 Chain A

Receptor sequence
>2aa7A (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
LSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQ
MIQVVKWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQF
LYFAPDLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLL
LLSTIPKDGLKSQAAFEEMRTNYIKELRKMVTKSGQSWQRFYQLTKLLDS
MHDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLY
FHR
3D structure
PDB2aa7 A Ligand-mediated Hydrogen Bond Network Required for the Activation of the Mineralocorticoid Receptor
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 1CA A L769 N770 A773 Q776 S810 F829 M845 M852 T945 L43 N44 A47 Q50 S84 F103 M119 M126 T215
External links
PDB RCSB:2aa7, PDBe:2aa7, PDBj:2aa7
PDBsum2aa7
PubMed15967794
UniProtP08235|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)

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