Structure of PDB 2a9i Chain A

Receptor sequence
>2a9iA (length=105) Species: 10090 (Mus musculus) [Search protein sequence]
KPLTPSTYIRNLNVGILRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFH
IRRFEALLQTGLSPTCELLFDWGTTNCTVGDLVDLLVQIELFAPATLLLP
DAVPQ
3D structure
PDB2a9i Cutting Edge: Molecular Structure of the IL-1R-Associated Kinase-4 Death Domain and Its Implications for TLR Signaling.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A K21 D24 K19 D22
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:2a9i, PDBe:2a9i, PDBj:2a9i
PDBsum2a9i
PubMed16177054
UniProtQ8R4K2|IRAK4_MOUSE Interleukin-1 receptor-associated kinase 4 (Gene Name=Irak4)

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